SN instructed about Pantoprazole or Protonix , it is used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. Pantoprazole may also be used in combination with antibiotics to treat ulcers caused by helicobacter pylori. Possible side effect / adverse reaction may include, Infection: Stomach acid plays a role in killing ingested bacteria. Use of pantoprazole may increase the chance of developing infections such as pneumonia, particularly in hospitalized patients. Gastrointestinal: abdominal pain , diarrhea , flatulence. Neurologic: headache. Serious side effect : Gastrointestinal: atrophic gastritis, clostridium difficile diarrhea; Hematologic: thrombocytopenia; Immunologic: Stevens-Johnson syndrome, toxic epidermal necrolysis; Musculoskeletal: Muscle disorders, bone fracture and infection, clostridium difficile infection, osteoporosis-related hip fracture, rhabdomyolysis; Renal: interstitial nephritis (rare), Nutrition: may reduce the absorption of important nutrients, vitamins and minerals, as well as medications.
