Instructed patient when should I call my clinician when on V.A.C. Therapy: immediately report to your clinician if you have any of these symptoms: fever over 102°, diarrhea, headache, sore throat, confusion, sick to your stomach or throwing up, dizziness or feel faint when you stand up, redness around the wound, skin itches or rash present, wound is sore, red or swollen, pus or bad smell from the wound, area in or around wound feels very warm.